Search Result

Search Results for " e. coli "

Targets

189

Compounds

Natural Products

3199

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T22269	Benzyldodecyldimethylammonium Chloride Dihydrate		Antibacterial
	Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aerugino...		Antibacterial
T36683	Vedaprofen	Quadrisol,PM 150,CERM 10202	COX , Antibacterial , Prostaglandin Receptor
	Vedaprofen (PM 150) inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM.		COX , Antibacterial , Prostaglandin Receptor
T9508	MONOCAPRYLIN	Sefsol 318,Glyceryl monocaprylate	Antibacterial
	Monocaprylin (Sefsol 318) is a monoglyceride of caprylic acid with an excellent antibacterial activity. Monocaprylin inhibits a variety of foodborne pathogenic and spoilage microorganisms and has the potential for an alt...		Antibacterial
T19794	Temafloxacin	Omniflox	Antibiotic
	Temafloxacin (Omniflox) is an antibiotic and antimycobacterial agent. It used to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.		Antibiotic
T82462	Enterotoxin STp (E. coli)
	Enterotoxin STp (E. coli), a heat-stable enterotoxin, is applicable in vaccine research [1].
T1389	Dyclonine hydrochloride	Dyclocaine hydrochloride,Dyclonine HCl	Sodium Channel , Antibacterial , Antifungal
	Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .		Sodium Channel , Antibacterial , Antifungal
T1293	Gatifloxacin	BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155	Topoisomerase , Antibacterial , Antibiotic
	Gatifloxacin (CG5501) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.		Topoisomerase , Antibacterial , Antibiotic
T39912	5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine	5'-O-DMT-dU	Others
	5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive dUTP nucleotidohydrolase (dUTPase) inhibitor(Ki > 1 mM) in E. coli. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted t...		Others
T13477	β-Glucuronidase-IN-1		Antibacterial
	β-Glucuronidase-IN-1 is an E. coli β-glucuronidase (β-glucuronidase) inhibitor with a potent, selective, non-competitive, and orally active IC50 and Ki value of 283 nM and 164 nM, respectively, against E. coli β-glucuron...		Antibacterial
T12126	MUT056399	Fab-001	Antibacterial
	MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli (IC50s of 12 nM and 58 nM, respectively).		Antibacterial
T77798	Sodium Nitrite	Nitrous acid, sodium salt	Others
	Sodium Nitrite (Nitrous acid, sodium salt) is a compound that is not easy to store and will oxidize to nitric acid if left in the air.Sodium Nitrite has a variety of functions, both oxidizing and reducing, and is very ve...		Others
TP1496L	P5 Ligand for Dnak and DnaJ acetate	p5 Ligand for Dnak and DnaJ acetate(209518-24-1 free base)	HSP
	p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40).		HSP
T33828	O-Succinylhomoserine	O-Succinyl-L-homoserine	Others
	O-Succinylhomoserine (O-Succinyl-L-homoserine) is an intermediate in the synthesis of cystathionine by E coli..		Others
TQ0018	6-Amino-5-azacytidine		Antibacterial
	6-Amino-5-azacytidine has an inhibitory of the growth of E. coli.		Antibacterial
T20936	Lauramine oxide	LDAO,Dimethylaurylamine oxide,Refan,Lauryldimethylamine oxide	Antibacterial
	Lauramine oxide (Refan) is effective against common bacteria such as E. coli and S. aureus, however it is non-denaturing and may be used to solubilize proteins.		Antibacterial
T6638	Retapamulin	SB-275833	ribosome , Antibacterial , Antibiotic
	Retapamulin (SB-275833), a Pleuromutilin Antibacterial, binds to both E. coli and S. aureus ribosomes with similar potencies (Kd: 3 nM).		ribosome , Antibacterial , Antibiotic
T10347L	Apidaecin IB acetate	Apidaecin IB acetate (123276-94-8 Free base)	Others
	Apidaecin IB acetate is an insect antibacterial peptide. The minimum concentration of apidaecin IB acetate against Escherichia coli (E. coli ML35, o18k1h7 and ATCC 25922) is 8 μM.		Others
T22387	NSC 55655	5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione	Others
	NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) possesses antimicrobial and antioxidant activities and inhibits the proliferation of B. subtilis, S. aureus, K. pneumonia, E. coli, S. typhi , A. niger and C...		Others
T32490	L-161240	L-161,240	Antibacterial
	L-161240 is an antimicrobial agent associated with lipid A biosynthesis with an IC50 value of 30 nM as determined by DEACET and a MIC value of 1-3 μg/ mL against wild-type E. coli.		Antibacterial
T11227L	Eravacycline dihydrochloride	TP-434-046,TP-434 dihydrochloride	Antibacterial
	Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).		Antibacterial
T11348	G907		Antibiotic
	G907 is a selective and potent antagonist of the small molecule ATP-binding cassette (ABC) transporter protein MsbA, with bactericidal activity, which traps MsbA in the inner lipopolysaccharide. G907 inhibits E. coli Msb...		Antibiotic
TP1663L	CysHHC10 acetate	CysHHC10 acetate(1408311-03-4 free base)	Antibacterial
	CysHHC10 acetate shows antibacterial activities against both Gram-positive and Gram-negative bacteria with MIC of 10.1, 20.2, 2.5, and 1.3 mM for E. coli, P. aeruginosa, S. aureus, and S. epidermidis, respectively.		Antibacterial
T10337	Antimicrobial Compound 1		Antibacterial
	Antimicrobial Compound 1 is an alkyl pyridinium compound with Tail 12C, Head 4-carboxyl. Antimicrobial Compound 1 exhibits antimicrobial activities against B. subtilis and E. coli.		Antibacterial
T1569	Tigecycline	GAR-936	ribosome , Antibacterial , Antibiotic , Autophagy
	Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome co...		ribosome , Antibacterial , Antibiotic , Autophagy
T5413	ML216	CID-49852229	DNA/RNA Synthesis
	ML216 (CID-49852229) is a small molecule inhibitor of BLM helicase (IC50: 1.8 μM). It showed 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s > 50 μM).		DNA/RNA Synthesis
T9727	2'-Fluoro-2'-Deoxyadenosine		Nucleoside Antimetabolite/Analog
	2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors ex...		Nucleoside Antimetabolite/Analog
T11876	LpxH-IN-AZ1		Antibacterial
	LpxH-IN-AZ1 is a potent inhibitor of the UDP-2,3-diacylglucosamine pyrophosphate hydrolase, LpxH, and sulfonylpiperazine compounds.LpxH-IN-AZ1 exhibits antimicrobial activity and inhibits Klebsiella pneumoniae with an IC...		Antibacterial
T77615	ND-011992	ND011992	Mitochondrial Metabolism , Antibacterial
	ND-011992 is a reversible and selective quinazoline inhibitor targeting quinone reductases and quinol oxidases.ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I. ND-011992 inhibits bo3 oxidase, bd-I oxidases and...		Mitochondrial Metabolism , Antibacterial
TP1773L	PGLa acetate		Antibacterial , Antibiotic
	PGLa acetate is a 21-residue member of the magainin family of antibiotic peptides.		Antibacterial , Antibiotic
T21831	UCM05	G28UCM	Fatty Acid Synthase
	UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) with efficacy against HER2+ breast cancer xenografts, including in cell lines resistant to anti-HER2 drugs [1]. Additionally, it functions as an inhibito...		Fatty Acid Synthase
T60247	Diethylamine NONOate diethylammonium salt	NOC-18 Diethylamine,DEA NONOate diethylamine	Antibiotic
	Diethylamine NONOate diethylammonium salt (DEA NONOate diethylamine) is a nitric oxide donor with antibacterial activity, a dispersant for preformed biofilms of Pseudomonas aeruginosa and inhibits the growth of E. coli. ...		Antibiotic
T36352	Suc-Leu-Tyr-AMC
	Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome (excitation max: 360 nm; em...
T41275	PF-04753299		Others
	PF-04753299 is a potent and selective inhibitor of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC), demonstrating bactericidal effects against gonococcal isolates. It exhibits inhibitory activity aga...		Others
T77675	TNKS-2-IN-1		PARP , Wnt/beta-catenin , Antibiotic
	TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the releas...		PARP , Wnt/beta-catenin , Antibiotic
T3097	Mycophenolic Acid Impurity	5,7-dihydroxy-4-methylphthalide	Others
	Mycophenolic Acid Impurity (5,7-dihydroxy-4-methylphthalide) is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part...		Others
T38164	MnTBAP chloride	Mn(III)TBAP
	MnTBAP chloride (Mn(III)TBAP) is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger that reduces the doubling time of SOD-E. coli by a factor of 2. MnTBAP chloride exhibits anti-inflammatory ...
T35449	α-(difluoromethyl)-DL-Arginine	DFMA,RMI 71897,α-(difluoromethyl)-DL-Arginine	Others
	α-(difluoromethyl)-DL-Arginine (RMI 71897) is an enzyma-activated, irreversible inhibitor of arginine decarboxylase for E. coli (Ki = 800 μM), Pseudomonas aeruginosa, and Klebsiella pneumoniae. At 0.01 mM, it has been sh...		Others
T14043	4-(tert-Butyl)-benzhydroxamic Acid		Others
	4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively, and it reduces the production of the virulence factor pyocyanin in P. aeruginosa with...		Others
T36594	4-Chloroguaiacol
	4-Chloroguaiaco (4-Chloro-2-methoxyphenol), a derivative of phenol, demonstrates antimicrobial efficacy, inhibiting Staphylococcus aureus and Escherichia coli with minimum inhibitory concentrations (MICs) of 110 μg/mL fo...
T27972	MAC173979	MAC-173979,MAC 173979
	MAC173979 inhibits E. coli de novo PABA biosynthesis and growth.
T26790	Bharangin
	Bharangin is a inhibitor of penicillinase enzyme in E coli.
T29677	Aerobactin
	Aerobactin, as a bacterial iron chelating agent (siderophore), can be found in E. coli. It is a virulence factor that can enable E. coli to sequester iron in iron-poor environments.
T79132	Du011
	Du011 is a biogenesis inhibitor of the E. coli polysaccharide capsule that specifically targets MprA, with potential applications in E. coli infection research [1].
T32778	Lipid X
	Lipid X is a monosaccharide precursor of E coli lipid A.
T32779	Lipid Y
	Lipid Y is a monosaccharide precursor of E coli lipid A.
T31854	Formylmethionyl-alanyl-leucine	Fmet-ala-leu
	Formylmethionyl-alanyl-leucine is formed by E coli ribosomal protein L10 gene.
TP2399	Palmitoyl tetrapeptide	Pam-ser-ser-asn-ala
	Palmitoyl tetrapeptide is an analog of the N-terminal part of lipoprotein from the outer membrane of E. coli.
T28423	PKUMDL-LTQ-301
	PKUMDL-LTQ-301 is a potent inhibitor of HipA toxin. PKUMDL-LTQ-301 also inhibits E. coli persistence.
T78200	BDM91270
	BDM91270 (compound 29) serves as an inhibitor of the E. coli AcrAB-TolC efflux pump, displaying an EC90 value of 0.6 μM against wild-type E. coli AcrB. It has applications in research on Escherichia coli drug resistance ...
T62773	OX11
	OX11 is a selective inhibitor of S. pneumoniae, P. aeruginosa and E. coli bacteria.

Compounds

Benzyldodecyldimethylammonium Chloride Dihydrate

T22269

Synonym:

Target: Antibacterial

Vedaprofen

T36683

Synonym: Quadrisol,PM 150,CERM 10202

Target: COX, Antibacterial, Prostaglandin Receptor

MONOCAPRYLIN

T9508

Synonym: Sefsol 318,Glyceryl monocaprylate

Target: Antibacterial

Enterotoxin STp (E. coli)

T82462

Synonym:

Target:

Dyclonine hydrochloride

T1389

Synonym: Dyclocaine hydrochloride,Dyclonine HCl

Target: Sodium Channel, Antibacterial, Antifungal

Gatifloxacin

T1293

Synonym: BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155

Target: Topoisomerase, Antibacterial, Antibiotic

5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine

Target: Antibacterial

MUT056399

T12126

Synonym: Fab-001

Target: Antibacterial

Sodium Nitrite

T77798

Synonym: Nitrous acid, sodium salt

Target: Others

p5 Ligand for Dnak and DnaJ acetate

TP1496L

Synonym: p5 Ligand for Dnak and DnaJ acetate(209518-24-1 free base)

Target: HSP

O-Succinylhomoserine

T33828

Synonym: O-Succinyl-L-homoserine

Target: Others

6-Amino-5-azacytidine

TQ0018

Synonym:

Target: Antibacterial

Lauramine oxide

T20936

Synonym: LDAO,Dimethylaurylamine oxide,Refan,Lauryldimethylamine oxide

Target: Antibacterial

Retapamulin

T6638

Synonym: SB-275833

Target: ribosome, Antibacterial, Antibiotic

Apidaecin IB acetate

T10347L

Synonym: Apidaecin IB acetate (123276-94-8 Free base)

Target: Others

NSC 55655

T22387

Synonym: 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione

Target: Antibacterial

Eravacycline dihydrochloride

T11227L

Synonym: TP-434-046,TP-434 dihydrochloride

Target: Antibacterial

Synonym: CysHHC10 acetate(1408311-03-4 free base)

Target: Antibacterial

Antimicrobial Compound 1

T10337

Synonym:

Target: Antibacterial

Tigecycline

T1569

Synonym: GAR-936

Target: ribosome, Antibacterial, Antibiotic, Autophagy

ML216

T5413

Synonym: CID-49852229

Target: DNA/RNA Synthesis

2'-Fluoro-2'-Deoxyadenosine

T9727

Synonym:

Target: Nucleoside Antimetabolite/Analog

LpxH-IN-AZ1

T11876

Synonym:

Target: Antibacterial

ND-011992

T77615

Synonym: ND011992

Target: Mitochondrial Metabolism, Antibacterial

PGLa acetate

TP1773L

Synonym:

Target: Antibacterial, Antibiotic

UCM05

T21831

Synonym: G28UCM

Target: Fatty Acid Synthase

Diethylamine NONOate diethylammonium salt

T60247

Synonym: NOC-18 Diethylamine,DEA NONOate diethylamine

Target: PARP, Wnt/beta-catenin, Antibiotic

Mycophenolic Acid Impurity

T3097

Synonym: 5,7-dihydroxy-4-methylphthalide

α-(difluoromethyl)-DL-Arginine

T35449

Synonym: DFMA,RMI 71897,α-(difluoromethyl)-DL-Arginine

Target: Others

4-(tert-Butyl)-benzhydroxamic Acid

Synonym: MAC-173979,MAC 173979

Formylmethionyl-alanyl-leucine

T31854

Synonym: Fmet-ala-leu

Target:

Palmitoyl tetrapeptide

TP2399

Synonym: Pam-ser-ser-asn-ala

Cat No.	Product Name	Synonyms	Targets
T41078	Lipopolysaccharides, Escherichiacoli	Lipopolysaccharide, E. coli O111:B4	Others
	Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) is a macromolecular component of the outer membrane of Gram-negative bacteria, consisting of three regions: lipid A, oligosaccharide core and O-specific polysacchari...		Others
T1313	Nitrofurantoin	Furadantine,Macrodantin,Furadonine	Antibacterial , Antibiotic
	Nitrofurantoin (Furadantine), an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoi...		Antibacterial , Antibiotic
T8384	Gatifloxacin hydrochloride	AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride)	Topoisomerase , Antibacterial , Antibiotic
	Gatifloxacin hydrochloride (AM-1155 hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, which can inhibit the bacterial enzyme DNA rotase and topoisomerase IV.		Topoisomerase , Antibacterial , Antibiotic
T1100	Polymyxin B Sulfate	Aerosporin,PMB,Polymyxin B sulphate,Polymyxin B sulfate (1404-26-8 free base),Poly-RX	Antibacterial , Antibiotic
	Polymyxin B Sulfate (Poly-RX) is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Po...		Antibacterial , Antibiotic
T13708	Glycol chitosan		Antibacterial
	Glycol chitosan is a chitosan derivative with hydrophilic ethylene glycol branches. Glycol chitosan inhibits E. coli, S. aureus, and S. enteritidis growths (MICs: 4 μg/mL, 32 μg/mL, and <0.5 μg/mL). It enhances membrane ...		Antibacterial
T19146	5,6-Dihydrouridine		Endogenous Metabolite
	5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea.		Endogenous Metabolite
T4913	Maleic acid		Endogenous Metabolite , Antibacterial
	Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of L. monocytogenes and E. coli.		Endogenous Metabolite , Antibacterial
TN2281	Sinapaldehyde	trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde	Antibacterial
	Sinapaldehyde (trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde) is a natural product. Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μ...		Antibacterial
T0710	L-Cycloserine	Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone	HIV Protease , GABA Receptor
	L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of gamma-aminobutyric acid (G...		HIV Protease , GABA Receptor
TN2898	Kaempferol-7,4'-dimethyl ether	3,5-Dihydroxy-4',7-dimethoxyflavone	Antioxidant , Antifection
	Kaempferol-7,4'-dimethyl ether is isolated from the rhizomes of Zingiber phillipseae and exhibits antioxidant activity against S. aureus and E. coli with MICs at 200 and 225 μg/ml, respectively.		Antioxidant , Antifection
T37267	Pachybasin		Antibacterial
	Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and...		Antibacterial
T4010	Juglone	5-Hydroxy-1,4-naphthoquinone,Regianin	DNA/RNA Synthesis , Antibacterial
	Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin fam...		DNA/RNA Synthesis , Antibacterial
T10933	D-Cysteine		Endogenous Metabolite , Antibacterial
	D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of the growth of E. coli. D-cysteine is mediated by D-amino acid oxidase to produce H2S, and is a neuroprotective agent against cerebellar ataxia. D-cystein...		Endogenous Metabolite , Antibacterial
T4788	L-Norvaline		Others , Endogenous Metabolite
	L-Norvaline is an arginase inhibitor and a non-proteinogenic branched-chain amino acid. L-Norvaline has previously been reported to be a natural component of an antifungal peptide of Bacillus subtilis. L-Norvaline and ot...		Others , Endogenous Metabolite
TN4927	Rupesin E		Antifection
	Rupesin E shows significant antibacterial activities against Escherichia coli.		Antifection
T10455	Bafilomycin B1		Others
	Bafilomycin B1, a macrolide antibiotic isolated from Streptomyces sp, acts as an inhibitor of K+-dependent ATPase of E. coli. It also inhibits Gram-positive bacteria and fungi.		Others
TN2809	22-Dehydroclerosterol		Antifection
	22-Dehydroclerosterol has antibacterial activity against against E. coli, S. aureus, and H. pylori.		Antifection
T80001	Majoranaquinone		Antibiotic
	Majoranaquinone demonstrates potent antibacterial activity against four Staphylococcus strains, one Moraxella strain, and one Enterococcus strain. It also acts as an effective efflux pump inhibitor in Escherichia coli AT...		Antibiotic
T72250	4aα,7α,7aα-Nepetalactone
	4aα,7α,7aα-Nepetalactone exhibits antibacterial properties, effectively inhibiting the growth of Escherichia coli (E. coli), Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi, and Enterococcus faecalis.
T80020	UDP-3-O-acyl-GlcNAc diammonium	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium	Endogenous Metabolite
	UDP-3-O-acyl-GlcNAc diammonium serves as a metabolite in E. coli, playing a critical role in the biosynthesis pathway of 3-deoxy-D-manno-octulosonate (KDO) [1].		Endogenous Metabolite
TN3978	Epitaraxerol		Antifection
	Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis.		Antifection
T75685	UDP-3-O-acyl-GlcNAc
	UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine), an E. coli metabolite, plays a role in the 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway [1].
T40436	N,N'-Diacetylchitobiose
	N,N'-Diacetylchitobiose, a dimer of β(1,4) linked N-acetyl-D glucosamine, is derived from the hydrolysis of chitin. This compound serves as an alternative carbon source for E. coli.
TN1538	Curzerenone		Caspase , Antifection
	Curzerenone holds great promise for use in chemopreventive and chemotherapeutic strategies, it has slightly effective against E. coli (IZ = 10.8 ± 0.52).		Caspase , Antifection
T38275	Kirromycin
	Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis. It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis. Kirromycin inhibits ...
TN5229	Vibralactone B		Antifection
	Vibralactone B shows antibacterial activity, it can inhibit significantly the growth of E. coli and Pseudomonas aeruginosa, with MBC values of 50 and 100 ug/mL, respectively.		Antifection
T39626	Orotidine 5′-monophosphate	Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate
	Orotidine 5′-monophosphate, a pyrimidine ribonucleoside, functions as an endogenous metabolite in human, E. coli, and mouse processes. It serves as an intermediate in uridine monophosphate (UMP) biosynthesis and is utili...
T83920	4-Trehalosamine
	4-Trehalosamine, a microbial metabolite identified in Streptomyces, exhibits antibiotic properties. Demonstrating efficacy in cup assays, it is active against E. coli, K. pneumoniae, and B. subtilis at concentrations of ...
T80331	XT-2 peptide
	XT-2 peptide, an antimicrobial agent sourced from the skin secretions of Xenopus tropicalis, exhibits potent activity against E. coli, with a minimum inhibitory concentration (MIC) of 8 μM [1].
TN3650	Chrysothol		Antifection
	Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. It also shows anti-cancer activity against human breast cancer cells.		Antifection
T83902	Polymyxin E1 sulfate	Colistin A sulfate
	Polymyxin E1, a peptide antibiotic and key component of the cationic lipopeptide antibiotic colistin, was initially extracted from B. polymyxa. It demonstrates effectiveness against P. aeruginosa and E. coli, with minimu...
T83918	Clazamycin A hydrochloride	NSC 332188
	Clazamycin A, a microbial metabolite and antibiotic derived from Streptomyces, exhibits efficacy against several bacteria, namely S. aureus, B. anthracis, B. subtilis, E. coli, and P. aeruginosa, with minimum inhibitory ...
T36815	Chevalone C
	Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml). ...
T38258	Phanerosporic Acid
	Phanerosporic acid is a fungal secondary metabolite originally isolated from P. chrysosporum that has antibacterial activity against B. cereus, B. subtilis, and E. coli and antifungal activity against S. cerevisiae, A. n...
TN1991	Norchelerythrine		Antifection
	Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug/mL. It exhibits strong antifeeding activity in a concentration-dependant manner wi...		Antifection
T80342	XT-4
	XT-4, an antimicrobial peptide originating from the skin secretions of Xenopus tropicalis, exhibits potent activity against E. coli, with a minimum inhibitory concentration (MIC) valued at 18 μM [1].
TN5014	Shoreic acid		Antifection , HSV
	Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, respectively, it also shows antifungal activity against C. albi...		Antifection , HSV
T83862	Bactobolin A hydrochloride	BN-183B
	Bactobolin A, a microbial metabolite initially derived from Pseudomonas, exhibits both antibiotic and anticancer properties. It demonstrates activity against various bacteria including S. aureus, S. epidermidis, S. faeca...
T38086	Neohydroxyaspergillic Acid
	Neohydroxyaspergillic acid is a fungal metabolite produced by A. sclerotiorum that has antibiotic and antifungal activities. It inhibits the growth of P. aeruginosa, M. smegmatis, S. aureus, E. coli, K. pneumoniae, B. my...
T80343	MCF
	MCF, an antimicrobial peptide originating from bee venom, exhibits activity against E. coli W 160-37, S. aureus 8530, and B. subtilis, with minimum inhibitory concentration (MIC) values of 35-45 μg/ml, 25-35 μg/ml, and 1...
T80330	XT-1
	XT-1, an antimicrobial peptide sourced from Xenopus tropicalis skin secretions, exhibits potent activity against S. aureus, E. coli, and C. albicans, with minimum inhibitory concentration (MIC) values of 5, 6, and 50 μM,...
T75439	Angustifoline hydrochloride
	Angustifoline hydrochloride, an alkaloid derived from Lupinus angustifolius L. extract, demonstrates antimicrobial efficacy, potentially exhibiting bacteriostatic effects against S. aureus, B. subtilis, E. coli, P. aerug...
T37442	Aspergillin PZ
	Aspergillin PZ is a fungal metabolite originally isolated from A. awamori. It induces morphological deformation of P. oryzae conidia when used at a concentration of 89 nM. Aspergillin PZ is active against S. epidermidis ...
TN4264	Isoapetalic acid		HIV Protease , Antifection
	Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell lines) and both Gram-positive bacteria(two Gram-positive ba...		HIV Protease , Antifection
TN4402	Labd-13-ene-8,15-diol		Antifection
	13(E)-Labd-13-ene-8alpha,15-diol shows antiviral and anticancer activity, it shows strong anti-HRV2 and HRV3 activity with a 50% inhibitory concentration (IC50) of 2.68 and 0.87 microg/mL,respectively; it also exhibits a...		Antifection
T83693	Magainin 2 TFA	MG2
	Magainin 2, a cationic peptide derived from the African clawed frog (X. laevis) skin, exhibits host defense and antimicrobial properties. This compound effectively inhibits a range of pathogens, including E. coli, K. pne...
T36417	Nargenicin	Antibiotic 47444
	Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive...

Natural Products

Lipopolysaccharides, Escherichiacoli

T41078

Synonym: Lipopolysaccharide, E. coli O111:B4

Target: Others

Nitrofurantoin

T1313

Synonym: Furadantine,Macrodantin,Furadonine

Target: Antibacterial, Antibiotic

Gatifloxacin hydrochloride

T8384

Synonym: AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride)

Target: Topoisomerase, Antibacterial, Antibiotic

Polymyxin B Sulfate

T1100

Synonym: Aerosporin,PMB,Polymyxin B sulphate,Polymyxin B sulfate (1404-26-8 free base),Poly-RX

Target: Antibacterial, Antibiotic

Glycol chitosan

T13708

Synonym:

Target: Antibacterial

5,6-Dihydrouridine

T19146

Synonym:

Target: Endogenous Metabolite

Maleic acid

T4913

Synonym:

Target: Endogenous Metabolite, Antibacterial

Sinapaldehyde

TN2281

Synonym: trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde

Target: Antibacterial

L-Cycloserine

T0710

Synonym: Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone

Target: HIV Protease, GABA Receptor

Kaempferol-7,4'-dimethyl ether

TN2898

Synonym: 3,5-Dihydroxy-4',7-dimethoxyflavone

Target: Antioxidant, Antifection

Pachybasin

T37267

Synonym:

Target: Antibacterial

Juglone

T4010

Synonym: 5-Hydroxy-1,4-naphthoquinone,Regianin

Target: DNA/RNA Synthesis, Antibacterial

D-Cysteine

T10933

Synonym:

Target: Endogenous Metabolite, Antibacterial

L-Norvaline

T4788

Synonym:

Target: Others, Endogenous Metabolite

22-Dehydroclerosterol

4aα,7α,7aα-Nepetalactone

T72250

Synonym:

Target:

UDP-3-O-acyl-GlcNAc diammonium

T80020

Synonym: UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium

Target: Endogenous Metabolite

N,N'-Diacetylchitobiose

Target: Caspase, Antifection

Orotidine 5′-monophosphate

T39626

Synonym: Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate

Synonym: Colistin A sulfate

Target:

Clazamycin A hydrochloride

Target: Antifection, HSV

Bactobolin A hydrochloride

T83862

Synonym: BN-183B

Target:

Neohydroxyaspergillic Acid

Angustifoline hydrochloride

Target: HIV Protease, Antifection

Labd-13-ene-8,15-diol

Synonym: Antibiotic 47444

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00699	BamA Protein, E. coli, Recombinant (His)	E. coli	P. pastoris (Yeast)
	BamA Protein, E. coli, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 30 kDa and the accession number is P0A940.
TMPY-03650	BirA Protein, E. coli, Recombinant (His & MBP)	E. coli	E. coli
	The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these prote...
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli)	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPJ-01463	IL-2 Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-2 Protein, Human, Recombinant (E. coli) is expressed in E. coli expression system. The accession number is P60568.
TMPY-00541	LON PROTEASE Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and natura...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of...
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)	Human	E. coli
	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i...
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ...
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-02798	NEIL1 Protein, Human, Recombinant (His)	Human	E. coli
	NEIL1 is a member of DNA glycosylases. DNA glycosylases are a family homologous to the bacterial Fpg/Nei family. They play a role in base excision repair which is the mechanism by which damaged bases in DNA are removed a...
TMPH-00624	Flagellin Protein, E. coli, Recombinant	E. coli	E. coli
	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 51.2 kD...
TMPY-02375	AcnB Protein, E. coli, Recombinant	E. coli	E. coli
	Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to Sox...
TMPH-00744	CsrA Protein, E. coli, Recombinant	E. coli	E. coli
	A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress...
TMPH-00696	OmpC Protein, E. coli, Recombinant	E. coli	E. coli
	Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) Supports colicin E5 entry in the absence of its major receptor OmpF.; (Microbial infection) A mixed OmpC-OmpF ...
TMPH-00731	RpoS Protein, E. coli, Recombinant	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and...
TMPH-00636	Hemolysin E, chromosomal Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells.
TMPH-00728	FliA Protein, E. coli, Recombinant	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. FliA Protein, E....
TMPH-00595	HtpG Protein, E. coli, Recombinant	E. coli	E. coli
	Molecular chaperone. Has ATPase activity.
TMPH-00745	TsaE Protein, E. coli, Recombinant	E. coli	E. coli
	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of thre...
TMPH-00750	YcbX Protein, E. coli, Recombinant (GST)	E. coli	E. coli
	YcbX Protein, E. coli, Recombinant (GST) is expressed in E. coli.
TMPJ-00819	Trp A Protein, E. coli, Recombinant	E. coli	E. coli
	Trp A Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27 KDa and the accession number is P0A877.
TMPH-00698	OmpA Protein, E. coli, Recombinant (His)	E. coli	E. coli
	OmpA Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 38.0 kDa and the accession number is P0A910.
TMPH-00575	GlpD Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor. GlpD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The pred...
TMPH-00578	NrdD Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. NrdD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag....
TMPH-00641	YTFE Protein, E. coli, Recombinant (GST)	E. coli	E. coli
	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions. YTFE Protein, E. coli, Recombinant (GST) is expressed in E. coli expression system with N-...
TMPH-00741	Rho Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase wh...
TMPH-00734	LuxS Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in respon...
TMPJ-00728	Beta-galactosidase Protein, E. coli, Recombinant	E. coli	E. coli
	β-galactosidase is an exoglycosidase which hydrolyzes the β-glycosidic bond formed between a galactose and its organic moiety. It may also cleave fucosides and arabinosides but with much lower efficiency. β-galactosides ...
TMPH-00752	YncE Protein, E. coli, Recombinant (His)	E. coli	E. coli
	YncE Protein, E. coli, Recombinant (His) is expressed in E. coli with C-terminal 6xHis tag. The predicted molecular weight is 36.3 kDa. Accession number: P76116
TMPH-00626	GPR Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. GPR Protein, E. coli, R...
TMPH-00738	TetR5 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline re...
TMPH-00612	MutL Protein, E. coli, Recombinant (His)	E. coli	E. coli
	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable co...
TMPH-00730	RpoS Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and...
TMPH-00648	LapB Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of prote...
TMPH-00602	MetC Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Primarily catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. Also exhibits cysteine desulfhydrase activity, producing sulfide from cysteine. In addition, under c...
TMPH-00660	NikR Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.
TMPH-00583	Rep Protein, E. coli, Recombinant (GST)	E. coli	E. coli
	Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in t...
TMPH-00555	LpxC Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
TMPH-00643	K99 fimbrial Protein, E. coli, Recombinant	E. coli	E. coli
	Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host orga...
TMPH-00599	LDCC Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Plays a role in lysine utilization by acting as a lysine decarboxylase.
TMPH-00594	HtpG Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Molecular chaperone. Has ATPase activity.
TMPH-00727	FliA Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.
TMPH-00732	RtcB Protein, E. coli, Recombinant (His)	E. coli	P. pastoris (Yeast)
	GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splici...
TMPH-00617	MazF Protein, E. coli, Recombinant (His)	E. coli	P. pastoris (Yeast)
	MazF Protein, E. coli, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 13.6 kDa and the accession number is P0AE70.
TMPH-00621	NfuA Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged ...
TMPH-00570	MsyB Protein, E. coli, Recombinant (His)	E. coli	Baculovirus Insect Cells
	Could participate in the normal pathway of protein export. MsyB Protein, E. coli, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession ...
TMPY-02390	SSPA Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Stringent starvation protein A (ssPA), a member of the GST superfamily, is an RNA polymerase-associated transcriptional activator for the lytic development of phage P1 and is essential for stationary phase-induced acid t...
TMPJ-00787	GUSB Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Beta-D-glucuronidase from E.coli is a highly specific enzyme in hydrolyzing glucuronides. Beta-D-glucuronidase (GLUase) activity can be measured as the rate of production of fluorescent methylumbelliferone (MU), resulti...
TMPH-00726	Ribokinase Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a compone...
TMPH-00708	DegP Protein, E. coli, Recombinant (His)	E. coli	P. pastoris (Yeast)
	DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm fo...
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